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“Heavenly Road”: The Qinghai–Tibet Railway

Yongfu SUN

Frontiers of Engineering Management 2020, Volume 7, Issue 2,   Pages 304-307 doi: 10.1007/s42524-019-0079-3

Abstract: Xiaobo WANG. [J]. Front. Eng, 2019, 6(1): 131-137.Peter REDFERN, Hua ZHONG. [J]. Front. Eng, 2017, 4(2): 193-200.Qixiang FAN. [J]. Front. Eng, 2017, 4(2): 231-237.Ming-zhou Liu,Cong-hu Liu,Mao-gen Ge,Yuan Zhang,Qing-hua Zhu. [J]. Front. Eng, 2016, 3(2): 144-146.Yu Zhao,Sheng-quan Wang,Ke-chao Zhu. [J]. Front. Eng, 2015, 2(1): 35-38.Ru-gui Chen,Jia-meng Chen. [J]. Front. Eng, 2014, 1(1): 52-61.An Wang. [J]. Front. Eng, 2014, 1(1): 13-17.

Keywords： permafrost protection     sustainable development     health guarantee system    

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Primary health care for all by 2020: The systematic reform of the medical and health system in China

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 3-7 doi: 10.1007/s11684-010-0024-7

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Reliability guarantee framework for the Sichuan–Tibet Railway

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 480-491 doi: 10.1007/s42524-021-0170-4

Abstract: This study proposes a novel reliability framework to guarantee the ideal operation state of the Sichuan–TibetGiven the fact that the Sichuan–Tibet Railway is a complex giant system, Nine-Connotation was summarizedThe proposed framework is composed of a resilience management system, an integrated technology system, and a dynamic reliability assessment system.It also shows the reliability transmission and control mechanism of the railway’s giant complex system

Keywords： Sichuan–Tibet Railway     operational efficiency     reliability guarantee     Nine-Connotation     implementation    

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Development of an integrated structural health monitoring system for bridge structures in operational

Xinqun ZHU, Hong HAO

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 3,   Pages 321-333 doi: 10.1007/s11709-012-0161-y

Abstract: This paper presents an overview of development of an integrated structural health monitoring system.The integrated system includes vibration and guided-wave based structural health monitoring.It integrates the real-time heterogeneous sensor data acquiring system, data analysis and interpretation, physical-based numerical simulation of complex structural system under operational conditions and structuralNumerical simulation and its implementation in laboratory show that the system is effective and reliable

Keywords： integrated structural health monitoring     operational conditions     vibration and guided wave    

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Frontier of continuous structural health monitoring system for short & medium span bridges and condition

Ayaho MIYAMOTO, Risto KIVILUOMA, Akito YABE

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 3,   Pages 569-604 doi: 10.1007/s11709-018-0498-y

Abstract: Bridge health monitoring using information technology and sensors is capable of providing more accuratesystem incorporating with the information and communication technologies for lifetime management ofexisting short and medium span bridges but also a continuous data collecting system designed for bridgehealth monitoring of mainly short and medium span bridges.system (called bus monitoring system) to be applied mainly to short and medium span bridges, along with

Keywords： condition assessment     short & medium span bridge     structural health monitoring(SHM)     long-term data collection     system     maintenance     bridge performance     information technology     loading vehicle(public bus)     in-situ<    

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Integration of current identity-based district-varied health insurance schemes in China: implications

Hai-Qiang Wang, Zhi-Heng Liu, Yong-Zhao Zhang, Zhuo-Jing Luo

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 79-84 doi: 10.1007/s11684-012-0179-5

Abstract:

With China’s great efforts to improve public health insurance, clear progress has been achievedtoward the ambitious full health insurance coverage strategy for all.The current health insurance schemes in China fall into three categories: urban employee basic healthinsurance scheme, urban resident scheme, and new rural cooperative medical system.Moreover, the reform of the “Hukou” (household register) system provides economical, official

Keywords： health insurance     urban employee basic health insurance scheme     urban-resident scheme     new rural cooperativemedical system    

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Design of structure health monitoring system of Taizhou Bridge

Tang Ke and Dai Pengfei

Strategic Study of CAE 2012, Volume 14, Issue 5,   Pages 14-18

Abstract:

A systematic description of the design of health monitoring system forThe system consists of 3 sub-systems of sensors, data acquisition and transmission, and data processing

Keywords： health monitoring system     wireless sensor     largescale bridge structure    

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Study of RDL-based data report in bridge structural health monitoring system

Zhang Xiaobin,Chen Weiguo

Strategic Study of CAE 2010, Volume 12, Issue 7,   Pages 110-112

Abstract: and high operability, therefore, the program can effectively analyze the data of bridge structural healthmonitoring system.

Keywords： structural health monitoring system     RDL     report definition language     data report    

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Framework and Application Strategy of Smart Proactive Health Service

Liang Chao , Wang Hua , Tang Lixu

Strategic Study of CAE 2023, Volume 25, Issue 5,   Pages 30-42 doi: 10.15302/J-SSCAE-2023.05.014

Abstract:
The innovative application of smart proactive health services is anproactive health intervention and management capabilities and provide high-quality health services fortrend, and proposes the concept of smart proactive health services.Moreover, the study constructs a technical system of smart proactive health services using a structureddigital literacy to reshape the atmosphere for service participation; (3) building a service standards system

Keywords： smart proactive health services     sports for health     technology system     application framework     construction    

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CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 322-338 doi: 10.1007/s11684-021-0901-2

Abstract: Immune-based therapies have experienced a pronounced breakthrough in the past decades as they acquired multiple US Food and Drug Administration (FDA) approvals for various indications. To date, six chimeric antigen receptor T cell (CAR-T) therapies have been permitted for the treatment of certain patients with relapsed/refractory hematologic malignancies. However, several clinical trials of solid tumor CAR-T therapies were prematurely terminated, or they reported life-threatening treatment-related damages to healthy tissues. The simultaneous expression of target antigens by healthy organs and tumor cells is partly responsible for such toxicities. Alongside targeting tumor-specific antigens, targeting the aberrantly glycosylated glycoforms of tumor-associated antigens can also minimize the off-tumor effects of CAR-T therapies. Tn, T, and sialyl-Tn antigens have been reported to be involved in tumor progression and metastasis, and their expression results from the dysregulation of a series of glycosyltransferases and the endoplasmic reticulum protein chaperone, Cosmc. Moreover, these glycoforms have been associated with various types of cancers, including prostate, breast, colon, gastric, and lung cancers. Here, we discuss how underglycosylated antigens emerge and then detail the latest advances in the development of CAR-T-based immunotherapies that target some of such antigens.

Keywords： cancer immunotherapy     chimeric antigen receptor     solid tumors     tumor-associated antigen     glycosylation     O-glycans     adoptive cell therapy    

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Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Strategic Study of CAE 2017, Volume 19, Issue 6,   Pages 44-51 doi: 10.15302/J-SSCAE-2017.06.007

Abstract:

This paper analyzes four aspects of the safety problems in tunnel lining structures: design and construction, environmental erosion, sudden natural disasters, and sudden accidents. A survey of underwater tunneling such as the Huangpu River’s cross-river tunnel and the underground traffic tunnel in Shanghai was carried out, and the status quo of China’s underwater tunnel lining structure was analyzed. Based on these analyses, countermeasures guaranteeing the long-life security of underwater tunnel structures are being sought regarding tunnel construction, structural performance degradation, sudden natural disasters, and sudden accidents. These countermeasures are being sought to effectively protect and ensure the service performance of the tunnel structures during their entire life cycle. These security measures can ensure the safe performance of the structure during its entire life cycle, even under long service times. This research can serve as a reference for enhancing the structural security of underwater tunnels and other major tunnel structures.

Keywords： underwater tunnels     service security     security guarantee countermeasures     long life     structural defects    

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Biomedical sensor technologies on the platform of mobile phones

Lin LIU, Jing LIU

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 2,   Pages 160-175 doi: 10.1007/s11465-011-0216-0

Abstract: biomedical practices, which play an important role in disease detection, diagnosis, monitoring, treatment, health

Keywords： biomedical sensor     pervasive technology     mobile phone     combined system     health management    

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Peacetime and Epidemic Combination Medical Materials Reserve System for Public Health Emergencies

Cai Jianping, Wang Jing

Strategic Study of CAE 2022, Volume 24, Issue 6,   Pages 107-115 doi: 10.15302/J-SSCAE-2022.07.005

Abstract:

 Establishing a medical materials reserve system that integratescrucial for promoting the medical materials support ability and improving the emergency management systemin China in case of public health emergencies.This study summarizes the development status of China's medical materials reserve system and analyzesMoreover, it expounds on the necessity and urgency for building a medical materials reserve system that

Keywords： public health emergencies     medical materials reserve system     normal time and emergency combination     basic    

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Educational Policy of Public Health Talents in China Under the Background of Comprehensive Health

Duan Zhiguang, Wang Tong, Li Xiaosong, Hu Yonghua, Liang Xiaofeng, Zeng Cheng,Ren Tao, Luo Huiming, Zhang Wenping, Xu Jianguo

Strategic Study of CAE 2019, Volume 21, Issue 2,   Pages 61-68 doi: 10.15302/J-SSCAE-2019.02.002

Abstract:

Under the ever-changing status of the global health and the rising ofare certain deficiencies and problems in the input, process, and output stages of the current public healthChina, and proposes a series of policy recommendations, including constructing a comprehensive public healthtalent training system that has Chinese characteristics and involves college education, postgraduateFurthermore, the government should fulfill its full responsibility in public health education reforms

Keywords： Comprehensive Health     public health     preventive medicine     personnel training     system    

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Public Health Emergency Command System of China

Xue Lan, Peng Zongchao, Zhong Kaibin, Lyu Xiaoli, Huang Yanzhong,Hu Yinglian, Kong Feng

Strategic Study of CAE 2021, Volume 23, Issue 5,   Pages 1-8 doi: 10.15302/J-SSCAE-2021.05.001

Abstract: This study aims to improve China’s public health emergency command system via investigating thehistory, current status, and challenges of the system.China’s public health emergency command system played a significant role in dealing with thesepublic health emergencies and has been increasingly improved; however, it still faces various challengesfor public health emergencies, advisory board, and central–local relations.

Keywords： public health     emergency command system     emergency response system evolution     coronavirus disease 2019 (    

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Title Author Date Type Operation

“Heavenly Road”: The Qinghai–Tibet Railway

Yongfu SUN

Journal Article

Primary health care for all by 2020: The systematic reform of the medical and health system in China

Journal Article

Reliability guarantee framework for the Sichuan–Tibet Railway

Journal Article

Development of an integrated structural health monitoring system for bridge structures in operational

Xinqun ZHU, Hong HAO

Journal Article

Frontier of continuous structural health monitoring system for short & medium span bridges and condition

Ayaho MIYAMOTO, Risto KIVILUOMA, Akito YABE

Journal Article

Integration of current identity-based district-varied health insurance schemes in China: implications

Hai-Qiang Wang, Zhi-Heng Liu, Yong-Zhao Zhang, Zhuo-Jing Luo

Journal Article

Design of structure health monitoring system of Taizhou Bridge

Tang Ke and Dai Pengfei

Journal Article

Study of RDL-based data report in bridge structural health monitoring system

Zhang Xiaobin,Chen Weiguo

Journal Article

Framework and Application Strategy of Smart Proactive Health Service

Liang Chao , Wang Hua , Tang Lixu

Journal Article

CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Journal Article

Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Journal Article

Biomedical sensor technologies on the platform of mobile phones

Lin LIU, Jing LIU

Journal Article

Peacetime and Epidemic Combination Medical Materials Reserve System for Public Health Emergencies

Cai Jianping, Wang Jing

Journal Article

Educational Policy of Public Health Talents in China Under the Background of Comprehensive Health

Duan Zhiguang, Wang Tong, Li Xiaosong, Hu Yonghua, Liang Xiaofeng, Zeng Cheng,Ren Tao, Luo Huiming, Zhang Wenping, Xu Jianguo

Journal Article

Public Health Emergency Command System of China

Xue Lan, Peng Zongchao, Zhong Kaibin, Lyu Xiaoli, Huang Yanzhong,Hu Yinglian, Kong Feng

Journal Article